DAMA Reserch Group invites you to attend the following talk:

Day, time: 14th February, 12:00.
Place: C6-E101, Campus Nord UPC.

Title: Integrating protein structure information into protein-protein interaction networks and its applications

Abstract:

In most network studies, protein–protein interactions are abstracted with a graph representation where proteins are represented as nodes and protein–protein interactions as edges. Such network representation is crucial for the comprehension of biological processes and protein function in the global sense. However, to characterize the interactions with respect to their structural and chemical properties and in particular to understand how the function is exerted, it is essential to include structural information in the networks. In this talk,  a new network model, protein-interface-protein networks, that integrate protein structure information with protein interactions, and efficient methods for building such networks will be discussed. Case studies on p53 tumor suppressor protein interactions, and drug-protein interactions will be presented to illustrate the  application of the network model.

Attila Gursoy
Professor
College of Engineering
Koc University, Istanbul

Visiting Scientist
Biomedical Informatics Group, PRBB, UPF