This chapter describes the main research activities in this Department. The information is organized along the four research lines presently pursued: "High Performance Computing"; "Design and Performance Evaluation of Broadband Integrated Communication Systems"; "Distributed Systems Architecture"; and "VLSI Systems Design". For each research group, we present a brief description of the most important working topics, including the best papers of each topic. The chapter is closing with the papers published in our Department since 1992.